You could easily find enough attractions to spend a week in each of these cities, but you can see the highlights of all three in a well-planned week.

The total travel time between Venice and Rome is only three and a half hours, so you can make the maximum use of your time.
Of course, youโ€™ll want to see the main sights, but do allow some time to stroll through a neighborhood or two and sit in a cafe to soak up the atmosphere.
For example, after youโ€™ve ridden the length of the Grand Canal and toured St. Markโ€™s Square and the Dogeโ€™s Palace, cross the World famous Rialto Bridge into the rabbit warren of narrow lanes in San Polo.
Here, youโ€™ll find mask makers, tiny shops, and artisan studios, as well as churches filled with art and squares where neighborhood children play soccer.
In Rome, after the Colosseum and St. Peterโ€™s, explore the streets of the former ghetto of Trastevere, south of the Vatican.
In Florence, follow your tours of the Pitti Palace art museums and gardens with a stroll through the Oltrarno neighborhood. Longer is better, of course, and with a day or two to spare, you can either see more of each of the โ€œBig Three,โ€ or you could make a stopover to see Bologna or hilltop Siena.